Follow the published publications of the project “AMResilience”

and contact group members if you want to know more, have any doubts or contribute to approach the challenge of AMR.

Publications of the consortium related to the AMResilience project

 

Wernli, D., Søgaard Jørgensen, P., Parmley, E. J., Troell, M., Majowicz, S., Harbarth, S., et al. (2020). Evidence for action: A One Health learning platform on interventions to tackle antimicrobial resistance. Lancet Infect. Dis. 3099, 1–5. doi: 10.1016/S1473-3099(20)30392-3

Abstract

Improving evidence for action is crucial to tackle antimicrobial resistance. The number of interventions for antimicrobial resistance is increasing but current research has major limitations in terms of efforts, methods, scope, quality, and reporting. Moving the agenda forwards requires an improved understanding of the diversity of interventions, their feasibility and cost–benefit, the implementation factors that shape and underpin their effectiveness, and the ways in which individual interventions might interact synergistically or antagonistically to influence actions against antimicrobial resistance in different contexts. Within the efforts to strengthen the global governance of antimicrobial resistance, we advocate for the creation of an international One Health platform for online learning. The platform will synthesise the evidence for actions on antimicrobial resistance into a fully accessible database; generate new scientific insights into the design, implementation, evaluation, and reporting of the broad range of interventions relevant to addressing antimicrobial resistance; and ultimately contribute to the goal of building societal resilience to this central challenge of the 21st century.

 

Léger, A., Lambraki, I., Graells, T., Cousins, M., Henriksson, P. J., Harbarth, S., … & Wernli, D. (2020). AMR-Intervene: a social–ecological framework to capture the diversity of actions to tackle antimicrobial resistance from a One Health perspective. Journal of Antimicrobial Chemotherapy, dkaa394, https://doi.org/10.1093/jac/dkaa394

 

Abstract

The global threat of antimicrobial resistance (AMR) requires coordinated actions by and across different sectors. Increasing attention at the global and national levels has led to different strategies to tackle the challenge. The diversity of possible actions to address AMR is currently not well understood from a One Health perspective. AMR-Intervene, an interdisciplinary social–ecological framework, describes interventions to tackle AMR in terms of six components: (i) core information about the publication; (ii) social system; (iii) bio-ecological system; (iv) triggers and goals; (v) implementation and governance; and (vi) assessment. AMR-Intervene provides a broadly applicable framework, which can inform the design, implementation, assessment and reporting of interventions to tackle AMR and, in turn, enable faster uptake of successful interventions to build societal resilience to AMR.

Previous Publications of group members on social-ecological and/or complex systems approach to AMR

  • Lhermie, G., Wernli, D., Jørgensen, P. S., Kenkel, D., Tauer, L. W., & Gröhn, Y. T. (2019). Global resistance to antimicrobials and their sustainable use in agriculture. The Lancet Planetary Health, 3(3), e109-e110.

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  • Jørgensen, P. S., Aktipis, A., Brown, Z., Carrière, Y., Downes, S., Dunn, R. R., . . ., Wernli D, Carroll SP. (2018). Antibiotic and pesticide susceptibility and the Anthropocene operating space. Nature Sustainability, 1(11), 632-641.

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  • Majowicz, S. E., Parmley, E. J., Carson, C., & Pintar, K. (2018). Identifying non-traditional stakeholders with whom to engage, when mitigating antimicrobial resistance in foodborne pathogens (Canada). BMC Research Notes, 11(1), 170.

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  • Wernli, D., Jørgensen, P. S., Harbarth, S., Carroll, S. P., Laxminarayan, R., Levrat, N., . . . Pittet, D. (2017). Antimicrobial resistance: The complex challenge of measurement to inform policy and the public. PLoS Medicine, 14(8), e1002378.

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  • Wernli, D., Jørgensen, P. S., Morel, C. M., Carroll, S., Harbarth, S., Levrat, N., & Pittet, D. (2017). Mapping global policy discourse on antimicrobial resistance. BMJ Global Health, 2(2), e000378.

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  • Jørgensen, P. S., Wernli, D., Carroll, S. P., Dunn, R. R., Harbarth, S., Levin, S. A., . . . Laxminarayan, R. (2016). Use antimicrobials wisely. Nature, 537(7619), 159-161.

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